In the state of Pennsylvania, I-80 is the main east-west Interstate-standard highway through central Pennsylvania. It runs from the Ohio state line near Sharon to the Delaware Water Gap Toll Bridge over the Delaware River,and is called the Confair Memorial Highway.
I-80 serves no major metropolitan areas in Pennsylvania directly. Spurs from I-80 run to State College, Williamsport, Scranton and Wilkes-Barre. I-80 intersects I-79 in Western Pennsylvania which connects with Erie (about 75 miles to the north) and Pittsburgh (about 55 miles to the south). Interstate 80's highest point (east of the Mississippi) is also located in Pennsylvania, near Exit 111 near Penfield, in Clearfield County.
In 2007, the Pennsylvania Turnpike Commission, combined with state legislature Act No. 44, initiated plans to enact a tolling system on the entire span of Interstate 80 throughout the Commonwealth of Pennsylvania. On October 15, 2007, PennDOT and the Pennsylvania Turnpike Commission signed a 50-year lease agreement, which will allow the Commission to maintain and, eventually, toll I-80.