In the state of Nevada, Interstate 80 runs northeast from the Lake Tahoe region near Reno to Battle Mountain. At Battle Mountain, it turns east to the salt flats of Utah via Elko. In Nevada, I-80 is routed along the Truckee and Humboldt rivers.
The stretch of I-80 through Nevada is largely desolate and mountainous. Services are limited compared to I-80 in other states.