In the state of Iowa, Interstate 80 runs from the I-80 bridge over the Missouri River east to the Quad Cities and the Fred Schwengel Memorial Bridge over the Mississippi River. It is the main east-west arterial freeway through south-central Iowa, and the main east-west Interstate in the state.
In Iowa I-80 serves the cities of Council Bluffs, Des Moines, Iowa City, and the Iowa portion of the Quad Cities - including Davenport and Bettendorf.
Interstate 80 holds a special place in the hearts of those at Drake University in Des Moines, Iowa. In 1999, Andrew Classen (Associate Professor of Trumpet and Director of Jazz Studies) composed the big band chart,"I-80 Shuffle", commemorating the great highway that passes through the university's hometown. The tune can be heard on the album Rush Hour by Classen's award-winning band, the Drake University Jazz Ensemble I . "I-80 Shuffle" is currently in print and published by C. L. Barnhouse Company in Oskaloosa, Iowa.